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Cushing's disease - Symptom

Alternative Names

Pituitary Cushing's disease

Symptoms:

Signs and tests:

Tests are done to confirm there is too much cortisol in the body, then to determine the cause.

These tests confirm too much cortisol:

These tests determine cause:

  • Brain MRI
  • Dexamethasone suppression test (high dose)
  • Serum ACTH levels
  • Test of corticotropin-releasing hormone, which acts on the pituitary gland to cause the release of ACTH (CRH test)
  • Test that measures ACTH levels in the veins that drain the pituitary gland (petrosal sinus sampling)
  • Reviewed last on: 3/18/2008
  • Elizabeth H. Holt, MD, PhD, Assistant Professor of Medicine, Section of Endocrinology and Metabolism, Yale University. Review provided by VeriMed Healthcare Network. Also reviewed byDavid Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

5. Stewart PM. The Adrenal Cortex. In: Kronenberg: Willliams Textbook of Endocrinology. Philadelphia, Pa: Saunders Elsevier; 2008:chap 14.