Deficiency - folic acid, Folic acid deficiency
Folate deficiency means you have a lower-than-normal amount of folic acid, a type of B vitamin, in your blood.
See also: Folic acid
Folic acid works along with vitamin B12 and vitamin C to help the body break down, use, and create new proteins. The vitamin helps form red blood cells and produce DNA, the building block of the human body, which carries genetic information.
Folic acid is a type of B vitamin. It is water-soluble, which means it cannot be stored in the body. Water-soluble vitamins dissolve in water. Leftover amounts of the vitamin leave the body through the urine.
Because folate is not stored in the body in large amounts, you need a continual supply of this vitamin through your diet to maintain normal levels.
You can get folate by eating green leafy vegetables and liver.
Causes of folate deficiency are:
Folic acid deficiency may cause:
Folate deficiency can be diagnosed with a blood test. Pregnant women usually have such blood tests during prenatal checkups.
Folic acid is also needed for the development of a healthy fetus. It plays an important part in the development of the fetus' spinal cord and brain. Folic acid deficiency can cause severe birth defects of the brain and spinal cord, known as neural tube defects.
The best way to get the daily requirement of all essential vitamins is to eat a balanced diet that contains a variety of foods from the food guide plate. Most people in the United States eat enough folic acid because it is plentiful in the food supply.
Folate occurs naturally in the following foods:
The Institute of Medicine's Food and Nutrition Board recommends that adults should have 400 micrograms of folate daily. Women capable of becoming pregnant should receive this amount with folic acid supplements, not just fortified foods, to ensure the proper daily intake.
Specific recommendations depend on a person's age, gender, and other factors (such as pregnancy). Many foods now have extra folic acid added to help prevent birth defects.
See Folic acid in diet for the full folic acid requirements by age group.
See Folic acid and birth defect prevention for more information on folic acid requirements during pregnancy.
Antony AC. Megaloblastic anemias. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 170.
Hamrick I, Counts SH. Vitamin and mineral supplements. Wellness and Prevention. 2008;35:729-747.
© 2011 University of Maryland Medical Center (UMMC). All rights reserved.
UMMC is a member of the University of Maryland Medical System,
22 S. Greene Street, Baltimore, MD 21201. TDD: 1-800-735-2258 or 1.866.408.6885