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Polycystic ovary disease - Treatment

Alternative Names

Polycystic ovaries; Polycystic ovarian syndrome (PCOS); Stein-Leventhal syndrome; Polyfollicular ovarian disease

Treatment:

Medications used to treat the symptoms of polycystic ovary disease include:

  • Birth control pills
  • Clomiphene citrate
  • Flutamide
  • Spironolactone

Treatment with clomiphene citrate causes the pituitary gland to produce more FSH. This causes the egg to mature and be released. Sometimes women need stronger fertility drugs to get pregnant.

In women with polycystic ovary disease who also have insulin resistance, glucophage (Metformin), a medication that makes cells more sensitive to insulin, has been shown to make ovulation normal.

Losing weight (which can be difficult) may help to reduce the high insulin levels in the blood. For women with this condition who are overweight, weight loss can reduce insulin resistance, stimulate ovulation, and improve fertility rates.

Expectations (prognosis):

Women who have this condition can get pregnant with the right surgical or medical treatments. Pregnancies are usually normal.

Complications:

  • Increased risk of endometrial cancer
  • Infertility
  • Obesity-related conditions, such as high blood pressure and diabetes
  • Possible increased risk of breast cancer

Calling your health care provider:

Call for an appointment with your health care provider if you have symptoms of this disorder.

  • Reviewed last on: 2/5/2008
  • Peter Chen, MD, Department of Obstetrics & Gynecology, University of Pennsylvania Medical Center, Philadelphia, PA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Katz VL, Lentz GM, Lobo RA, Gershenson DM. Comprehensive Gynecology. 5th ed. Philadelphia, Pa: Mosby;2007.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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