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Colloid nodular goiter - Overview

Alternative Names

Endemic goiter

Definition of Colloid nodular goiter:

Colloid nodular goiter is the enlargement of an otherwise normal thyroid gland.

See also: Goiter

Causes, incidence, and risk factors:

Colloid nodular goiters are also known as endemic goiters. They are usually caused by not getting enough iodine in the diet.

Colloid nodular goiters tend to occur in certain areas with iodine-poor soil. These areas are usually away from the sea coast. An area is defined as endemic for goiter if more than 10% of children ages 6 - 12 have goiters.

Certain things in the environment may also cause thyroid enlargement.

Small- to moderate-sized goiters are relatively common in the United States. The Great Lakes, Midwest, and Intermountain regions were once known as the "goiter belt." The routine use of iodized table salt now helps prevent this deficiency.

Risk factors for colloid nodular goiters include:

  • Being over age 40
  • Being female
  • Having a family history of goiter
  • Living in an area where there is endemic iodine deficiency
  • Not getting enough iodine in your diet
  • Reviewed last on: 6/17/2008
  • Elizabeth H. Holt, MD, PhD, Assistant Professor of Medicine, Section of Endocrinology and Metabolism, Yale University. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
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