Testicular failure - Overview
Primary hypogonadism - male
Definition of Testicular failure:
Testicular failure is when the testicles cannot produce sperm or male hormones.
Causes, incidence, and risk factors:
Testicular failure is uncommon. Causes include:
- Certain drugs, including glucocorticoids, ketoconazole, and opioids
- Chromosome problems
- Diseases that affect the testicle, including mumps, orchitis, and testicular cancer
- Injury to the testicles
- Testicular torsion
The following things increase the risk for testicular failure:
- Reviewed last on: 6/28/2011
- Ari S. Eckman, MD, Chief, Division of Endocrinology, Diabetes and Metabolism, Trinitas Regional Medical Center, Elizabeth, NJ. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
Bhasin S. Testicular disorders. In: Kronenberg HM, Shlomo M, Polonsky KS, Larsen PR, eds. Williams Textbook of Endocrinology. 11th ed. Philadelphia, Pa: Saunders Elsevier; 2008:chap 18.
Bhasin S, Cunningham GR, Hayes FJ, et al. Testosterone therapy in adult men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2006 Jun;91(6):1995-2010.
The information provided herein should not be used during any medical emergency or for the
diagnosis or treatment of any medical condition. A licensed medical professional should be
consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all
medical emergencies. Links to other sites are provided for information only -- they do not
constitute endorsements of those other sites. © 1997-
A.D.A.M., Inc. Any duplication or distribution of the information contained herein is
© 2011 University of Maryland Medical Center (UMMC). All rights reserved.
UMMC is a member of the University of Maryland Medical System,
22 S. Greene Street, Baltimore, MD 21201. TDD: 1-800-735-2258 or 1.866.408.6885