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Multiple Endocrine Neoplasia Type I - Symptom
Alternative Names
Wermer syndrome; MEN I
Symptoms:
Symptoms vary greatly from person to person. They may include:
- Abdominal pain
- Burning, aching, or hunger discomfort in the upper abdomen or lower chest that is relieved by antacids, milk, or food
- Black, tarry stools
- Nausea and vomiting
- Bloated feeling after meals
- Weakness
- Headache
- Vision problems
- Loss of coordination
- Anxiety
- Mental changes or confusion
- Coma (if hypoglycemia is untreated)
- Loss of appetite
- Muscle pain
- Fatigue
- Sensitivity to the cold
- Unintentional weight loss
- Low blood pressure
- Loss of underarm or pubic hair
- In women, cessation of menses, infertility, or failure to produce breast milk
- In men, decreased sexual interest, loss of body or facial hair
Signs and tests:
Tests to diagnose MEN I may include:
- MRI of abdomen
- MRI of the head
- CT of abdomen
- Cranial CT scan
- Parathyroid biopsy
- Insulin test
- Fasting blood sugar
- Serum glucagon
- Serum gastrin
- Serum calcium
- Serum parathyroid hormone
- Serum prolactin
- Serum thyroid stimulating hormone (rarely used)
- Cortisol
- Serum adrenocorticotropic hormone
- Serum luteinizing hormone
- Serum follicle stimulating hormone
- Reviewed last on: 10/25/2006
- Robert Hurd, M.D., Department of Biology, College of Arts and Sciences, Xavier University, Cincinnati, OH. Review provided by VeriMed Healthcare Network.
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