Sipple syndrome; MEN II
The symptoms may vary. However, they are similar to those of:
To diagnose this condition, the health care provider looks for a mutation in the RET gene. This can be done with a blood test. Additional tests are done to determine which hormones are being overproduced.
A physical examination may reveal:
Imaging tests used to identify tumors may include:
Blood tests are used to evaluate the function of each endocrine gland. The following tests may be performed:
Other tests or procedures that may be done include:
Kronenberg HM. Polyglandular disorders. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007: chap 250.
National Comprehensive Cancer Network Clinical Practice Guidelines in Oncology: Neuroendocrine Tumors. National Comprehensive Cancer Network; 2009. Version 2.2009.
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