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Multiple endocrine neoplasia (MEN) II - Symptom

Alternative Names

Sipple syndrome; MEN II

Symptoms:

The symptoms may vary. However, they are similar to those of:

Signs and tests:

To diagnose this condition, the health care provider looks for a mutation in the RET gene. This can be done with a blood test. Additional tests are done to determine which hormones are being overproduced.

A physical examination may reveal:

Imaging tests used to identify tumors may include:

Blood tests are used to evaluate the function of each endocrine gland. The following tests may be performed:

Other tests or procedures that may be done include:

  • Reviewed last on: 3/2/2010
  • David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Kronenberg HM. Polyglandular disorders. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007: chap 250.

National Comprehensive Cancer Network Clinical Practice Guidelines in Oncology: Neuroendocrine Tumors. National Comprehensive Cancer Network; 2009. Version 2.2009.

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