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Cushing syndrome due to adrenal tumor - Overview

Alternative Names

Adrenal tumor - Cushing syndrome

Definition of Cushing syndrome due to adrenal tumor:

Cushing syndrome due to adrenal tumor is an endocrine system disorder that occurs when there is a tumor of the adrenal gland releasing excess amounts of the hormone cortisol.

Causes, incidence, and risk factors:

Cushing syndrome is caused by constant, high levels of the steroid hormone cortisol. A tumor on one of the adrenal glands causes about 15% of all cases of Cushing syndrome. Adrenal tumors release cortisol.

Adrenal tumors may be noncancerous (benign) or cancerous (malignant).

Noncancerous tumors that may cause Cushing syndrome include:

  • Adrenal adenomas
  • Micronodular hyperplasia

Cancerous tumors that may cause Cushing syndrome include:

Adrenal tumors are rare. They may develop in anyone at any age, but are much more common in adults. They are found in women more often than men.

See also:

  • Reviewed last on: 3/18/2008
  • Elizabeth H. Holt, MD, PhD, Assistant Professor of Medicine, Section of Endocrinology and Metabolism, Yale University. Review provided by VeriMed Healthcare Network. Also reviewed byDavid Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Stewart PM. The adrenal cortex. In: Kronenberg HM, Melmed S, Polonsky KS, Larsen PR. Williams Textbook of Endocrinology. 11th ed. Philadelphia, PA: Elsevier; 2008:chap 14.

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