Gouty arthritis - acute; Gout - acute; Hyperuricemia; Tophaceous gout; Tophi; Podagra; Gout - chronic; Chronic gout; Acute gout; Acute gouty arthritis
Gout is a kind of arthritis that occurs when uric acid builds up in blood and causes joint inflammation.
Gout is caused by having higher-than-normal levels of uric acid in your body. This may occur if:
If too much uric acid builds up in the fluid around the joints (synovial fluid), uric acid crystals form. These crystals cause the joint to swell up and become inflamed.
The exact cause is unknown. Gout may run in families. It is more common in men, in women after menopause, and those who drink alcohol. People who take certain medicines, such as hydrochlorothiazide and other water pills, may have higher levels of uric acid in the blood.
The condition may also develop in people with:
The condition may occur after taking medicines that interfere with the removal of uric acid from the body.
Wilson JF. In the clinic. Gout. Ann Intern Med. 2010 Feb 2;152(3):ITC21.
Richette P, Bardin T. Gout. Lancet. 2010 Jan 23;375(9711):318-28.
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