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Osteoarthritis - Overview

Alternative Names

Hypertrophic osteoarthritis; Osteoarthrosis; Degenerative joint disease; DJD; OA; Arthritis - osteoarthritis

Definition of Osteoarthritis:

Osteoarthritis (OA) is the most common joint disorder.

Causes, incidence, and risk factors:

Osteoarthritis is caused by 'wear and tear' on a joint.

  • Cartilage is the firm, rubbery tissue that cushions your bones at the joints, and allows bones to glide over one another.
  • Cartilage can break down and wear away. As a result, the bones rub together, causing pain, swelling, and stiffness.
  • Bony spurs or extra bone may form around the joint, and the ligaments and muscles around the hip become weaker and stiffer.

Often, the cause of OA is unknown. It is mainly related to aging. The symptoms of OA usually appear in middle age. Almost everyone has some symptoms by age 70. However, these symptoms may be minor. Before age 55, OA occurs equally in men and women. After age 55, it is more common in women.

Other factors can also lead to OA.

  • OA tends to run in families
  • Being overweight increases the risk of OA in the hip, knee, ankle, and foot joints
  • Fractures or other joint injuries can lead to OA later in life
  • Long-term overuse at work or in sports can lead to OA

Medical conditions that can lead to OA include:


Osteoarthritis
  • Reviewed last on: 10/28/2010
  • David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Gregory PJ, Sperry M, Wilson AF. Dietary supplements for osteoarthritis. Am Fam Physician. 2008;77:177-184.

Hunter DJ. In the clinic: Osteoarthritis. Ann Intern Med. 2007;147(3):ITC8-1-ITC8-16.

Hunter DJ, Lo GH. The management of osteoarthritis: an overview and call to appropriate conservative treatment. Med Clin North Am. 2009;93:127-43, xi.

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