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Note: There may be no symptoms.
A physical exam can show limited range of motion, grating of a joint with motion, joint swelling, and tenderness.
An x-ray of affected joints will show loss of the joint space, and in advanced cases, wearing down of the ends of the bone and bone spurs.
Harris ED, Budd RC, Genovese MC, Firestein GS, Sargent JS, Sledge CB, Kelley's Textbook of Rheumatology , 7th ed. St. Louis, MO; W.B. Saunders; 2005.
US Food and Drug Administration. FDA Announces Series of Changes to the Class of Marketed Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) . Rockville, MD: National Press Office; April 7, 2005. Press Release P05-16.
US Food and Drug Administration. FDA Issues Public Health Advisory Recommending Limited Use of Cox-2 Inhibitors . Rockville, MD: National Press Office; December 23, 2004. Talk Paper T04-61.
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