Symptoms:

Skin symptoms may include:

• Blanching, blueness, or redness of fingers and toes in response to heat and cold (Raynaud's phenomenon)
• Hair loss
• Skin hardness
• Skin is abnormally dark or light
• Skin thickening and shiny hands and forearm
• Small white lumps beneath the skin
• Tight and mask-like facial skin
• Ulcerations on fingertips or toes

Bone and muscle symptoms may include:

• Joint pain
• Numbness and pain in the feet
• Pain, stiffness, and swelling of fingers and joints
• Wrist pain

Breathing problems may include:

• Dry Cough
• Shortness of breath
• Wheezing

Digestive tract problems may include:

• Bloating after meals
• Constipation
• Diarrhea
• Difficulty swallowing
• Esophageal reflux or heartburn
• Weight loss

Additional symptoms associated with this disease include:

• Eye burning, itching, and discharge

Signs and tests:

Examination of the skin may show tightness, thickening, and hardening.

Tests may include:

• Antinuclear antibody
• Chest x-ray
• CT scan of the lungs
• Echocardiogram
• ESR
• Rheumatoid factor
• Urinalysis
• Pulmonary function studies
• Skin biopsy