Symptoms:

• Skin lesions
  • Papule (small, solid, and raised lesion)
  • Red or purple colored
  • Located on the legs, hands, or other parts of the body
• Fingers that change color (blue fingers or toes)
• Tissue death due to lack of oxygen
  • Pain or tenderness in the area
  • Skin redness
  • Ulcers that do not heal
• Joint pain
• Abdominal pain
• Pain, numbness, tingling in an arm, leg, or other body area
• Changes or decrease in function of an arm, leg, or other body area
• Fever

Additional symptoms that may be associated with this disease:

• Weakness
• Swallowing difficulty
• Speech impairment
• Leg pain
• Muscle contractions
• Muscle atrophy
• Movement difficulty
• Painful menstruation
• Hoarseness or changing voice
• Fatigue
• Pupils that are different size
• Eyelid drooping

Note: Symptoms vary depending on the location of the affected vessels.

Signs and tests:

The doctor will perform a physical exam. A neurological examination may show signs of nerve damage.

Tests that may be done include:

• Biopsy of the muscle, organ, tissue or nerve biopsy
• Chest x-ray
• Sedimentation rate
• Urinalysis
• Hepatitis blood test
• Blood test for antibodies against neutrophils (ANCA antibodies)