Definition of Drug-induced lupus erythematosus:

Drug-induced lupus erythematosus is an autoimmune disorder that is brought on by a reaction to medication.

See also: Systemic lupus erythematosus (SLE)

Causes, incidence, and risk factors:

Drug-induced lupus erythematosus is similar to systemic lupus erythematosus (SLE). It is an autoimmune disorder, which means the body mistakenly attacks healthy tissue. It is caused by a hypersensitivity reaction to a medication.

The most common medications known to cause drug-induced lupus include: isoniazid, hydralazine, and procainamide. Other medications known to cause drug-induced lupus, include:

• Anti-seizure medications
• Capoten
• Chlorpromazine
• Etanercept
• Infliximab
• Methyldopa
• Minocycline
• Penicillamine
• Quinidine
• Sulfasalazine

Symptoms tend to occur after taking the drug for at least 3 to 6 months.

Persons with drug-induced lupus erythematosus may have symptoms that affect the joints (arthritis), heart, and lungs. Other symptoms associated with SLE, such as lupus nephritis and nervous system (neurological) disease, are rare.