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Diabetes insipidus - central - Treatment

Alternative Names

Central diabetes insipidus

Treatment:

The cause of the underlying condition should be treated.

Vasopressin (desmopressin) will be given either as a nasal spray, tablets by mouth, or injections under the skin. This controls the urine output and fluid balance and prevents dehydration.

In mild cases, drinking more water may be all that is needed. If the thirst mechanism is not working (for example, if the hypothalamus is damaged), a prescription for a certain amount of water intake may also be needed (usually 2-2.5 L per day) to ensure proper hydration.

Expectations (prognosis):

The outcome depends on the underlying disorder. If treated, diabetes insipidus does not cause severe problems or result in early death.

Complications:

  • Dehydration
  • Electrolyte imbalance
  • Confusion and changes in mental status may develop if the condition is not treated.

All patients with diabetes insipidus should wear a medic alert bracelet or necklace to alert care givers to this condition in an emergency situation.

Calling your health care provider:

Call your health care provider if symptoms indicate diabetes insipidus may be present.

  • Reviewed last on: 7/28/2008
  • Robert Cooper, MD, Endocinology Specialist  and Chief of Medicine, Holyoke Medical Center, Assistant Professor of Medicine, Tufts University School of Medicine, Boston MA Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Bringhurst FR, Demay MB, Kronenberg HM. Disorders of Mineral Metabolism. In: Kronenberg HM, Schlomo M, Polansky KS, Larsen PR, eds. Williams Textbook of Endocrinology. 11th ed. St. Louis, Mo: WB Saunders; 2008: chap. 27.

Robinson AG, Verbalis JG. Posterior Pituitary. In: Kronenberg HM, Schlomo M, Polansky KS, Larsen PR, eds. Williams Textbook of Endocrinology. 11th ed. St. Louis, Mo: WB Saunders; 2008: chap. 9.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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