Nephropathy - IgA; Berger's disease
The goal of treatment is to relieve symptoms and prevent or delay chronic renal failure.
Medicines may be given to control high blood pressure and swelling (edema). Angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) are used. Controlling blood pressure is the most important measure to delay kidney damage.
Corticosteroids, other immunosuppressive drugs, and fish oil have also been used to treat this disorder.
Salt and fluids may be restricted to control swelling. A low to moderateprotein diet may be recommended in some cases.
Some people will need to take medicines to lower their cholesterol.
Eventually, many patients must be treated for chronic kidney disease.
For additional information and support, see the IgA Nephropathy Support Network website (
IgA nephropathy progresses slowly. In many cases, it does not progress at all. High blood pressure, large quantities of protein in the urine, and increased BUN or creatinine levels (blood tests that reflect kidney functioning) indicate a higher risk for progression of the disorder.
About 25% of adults with IgA nephropathy develop end-stage kidney failure within about 25 years.
Call your health care provider if you have bloody urine or if your urine output decreases.
In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 122
© 2011 University of Maryland Medical Center (UMMC). All rights reserved.
UMMC is a member of the University of Maryland Medical System,
22 S. Greene Street, Baltimore, MD 21201. TDD: 1-800-735-2258 or 1.866.408.6885