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Malignant hypertension - Overview

Alternative Names

Accelerated hypertension; Arteriolar nephrosclerosis; Nephrosclerosis - arteriolar; Hypertension - malignant; High blood pressure - malignant

Definition of Malignant hypertension:

Malignant hypertension is a sudden and rapid development of extremely high blood pressure. The lower (diastolic) blood pressure reading, which is normally around 80 mmHg, is often above 130 mmHg.

Causes, incidence, and risk factors:

The disorder affects about 1% of people with high blood pressure, including both children and adults. It is more common in younger adults, especially African American men. It also occurs in women with toxemia of pregnancy, and persons with kidney disorders or collagen vascular disorders.

You are at high risk for malignant hypertension if you have had kidney failure or renal hypertension caused by renal artery stenosis.

  • Reviewed last on: 4/20/2009
  • Jacob L. Heller, MD, Emergency Medicine, Virginia Mason Medical Center, Seattle, Washington, Clinic. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Badr KF, Brenner BM. Vascular injury to the kidney. In: Fauci A , Kasper D, Longo DL, et al, eds. Harrison's Principals of Internal Medicine. 17th ed. New York, NY: McGraw Hill; 2008:chap 280.

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