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Malignant hypertension - Treatment

Alternative Names

Accelerated hypertension; Arteriolar nephrosclerosis; Nephrosclerosis - arteriolar; Hypertension - malignant; High blood pressure - malignant

Treatment:

You will need to stay in the hospital until the severe high blood pressure is under control. Medications will be given through a vein to reduce your blood pressure.

If there is fluid in your lungs, you will be given medicines called diuretics, which help the body remove fluid. Your doctor will consider giving you medications to protect the heart if there is evidence of heart damage.

After the severe high blood pressure is brought under control, blood pressure medicines taken by mouth can control blood pressure. Your medication may need to be changed sometimes. High blood pressure can be difficult to control.

Expectations (prognosis):

Many body systems are at serious risk from the extreme rise in blood pressure. Many organs, including the brain, eyes, blood vessels, heart, and kidneys may be damaged.

The blood vessels of the kidney are very likely to be damaged by pressure. Kidney failure may develop, which may be permanent and need dialysis (kidney machine).

If treated right away, malignant hypertension can often be controlled without causing permanent problems. If it is not treated right away, complications may be severe and life-threatening.

Complications:

  • Brain damage
  • Heart damage, including:
    • Heart attack
    • Angina (chest pain due to narrowed blood vessels or weakened heart muscle)
    • Heart rhythm disturbances
  • Kidney failure
  • Permanent blindness
  • Pulmonary edema (fluid in the lungs)

Calling your health care provider:

Go to the emergency room or call your local emergency number (such as 911) if you have symptoms of malignant hypertension. This is an emergency condition and it can be life-threatening.

Call your health care provider if you know you have poorly controlled high blood pressure.

  • Reviewed last on: 4/1/2011
  • Jacob L. Heller, MD, MHA, Emergency Medicine, Virginia Mason Medical Center, Seattle, Washington. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Badr KF, Brenner BM. Vascular injury to the kidney. In: Fauci A , Kasper D, Longo DL, et al, eds. Harrison's Principals of Internal Medicine. 17th ed. New York, NY: McGraw Hill; 2008:chap 280.

Shayne P, Stettner E. Hypertension. In: Wolfson AB, Hendey GW, Ling LJ, et al, eds. Harwood-Nuss' Clinical Practice of Emergency Medicine. 5th ed. Philadelphia, Pa: Lippincott Williams & Wilkins; 2009:chap 89.

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