Definition of Distal renal tubular acidosis:

Distal renal tubular acidosis is a disease that occurs when the kidneys don't remove acid properly into the urine, leaving the blood too acidic (called acidosis).

Causes, incidence, and risk factors:

Your kidneys normally regulate your body's pH by controlling acids.

Distal renal tubular acidosis (Type I RTA) is caused by a defect in the kidney tubes that causes acid to build up in the bloodstream.

Type I RTA is caused by a variety of conditions, including:

• Autoimmune diseases
• Drugs such as amphotericin B, lithium, and analgesics
• Hereditary disorders