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Minimal change nephrotic syndrome; Nil disease; Lipoid nephrosis; Idiopathic nephrotic syndrome of childhood
There may be symptoms of nephrotic syndrome:
Minimal change disease does not reduce the amount of urine produced. It rarely progresses to kidney failure.
The doctor may not be able to see any obvious outward signs of the disease, other than swelling. Blood and urine tests reveal signs typical of nephrotic syndrome, including:
A kidney biopsy and examination of the tissue with an electron microscope can show signs of minimal change disease. An immunofluorescence exam of the biopsied kidney tissue is negative.
Appel GB. Glomerular disorders and nephrotic syndromes. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007: chap 122.
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