Treatment:

The goal is to restore the normal pH (acid-base level) and electrolyte balance to the body. This will indirectly correct bone disorders and reduce the risk of osteomalacia and osteopenia in adults.

Some adults may need no treatment. All children need alkaline medication to prevent bone disease (rickets in particular) and to allow normal growth. The underlying cause should be corrected if it can be found.

Alkaline medications include sodium bicarbonate and potassium citrate. They correct the acidic condition of the body and correct low potassium levels. Thiazide diuretics may indirectly decrease bicarbonate loss but may increase the low potassium levels.

Vitamin D and calcium supplements may be needed to help reduce skeletal deformities resulting from osteomalacia or rickets.

Expectations (prognosis):

Although the underlying cause of proximal renal tubular acidosis may go away by itself, the effects and complications can be permanent or life-threatening. Treatment is usually successful.

Complications:

• Electrolyte imbalances, such as hypokalemia
• Osteomalacia
• Rickets

Calling your health care provider:

Call your health care provider if you have symptoms of proximal renal tubular acidosis.

Get medical help immediately if you develop any of the following emergency symptoms:

• Decreased alertness or orientation
• Decreased consciousness
• Seizures