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End-stage kidney disease - Symptom

Alternative Names

Renal failure - end stage; Kidney failure - end stage; ESRD

Symptoms:

Decreased alertness
Decreased sensation in the hands, feet, or other areas
Decreased urine output
Easy bruising or bleeding
Fatigue
Frequent hiccups
General ill feeling
Headache
Increased skin color (pigmentation)
Itching
May have blood in the vomit or stools
Muscle twitching or cramps
Nail abnormalities
Nausea or vomiting
No urine output
Seizures
Skin may appear yellow or brown
Unintentional weight loss

Signs and tests:

There may be a long history of chronic kidney failure, which has progressed. The urine volume may decrease or urine production may stop totally. Signs of complications commonly are present.

Tests may include:

Creatinine and BUN levels
Creatinine clearance

Kidney anatomy

Reviewed last on: 11/15/2008
Parul Patel, MD, Private practice specializing in Nephrology, Kidney and Pancreas Transplantation, affiliated with California Pacific Medical Center Department of Transplantation, San Francisco, CA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Tolkoff-Rubin N. Treatment of irreversible renal failure. In: Goldman L, Ausiello D, eds. Goldman: Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007: chap 133.

Mitch WE. Chronic kidney disease. In: Goldman L, Ausiello D, eds. Goldman: Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007: chap 131.

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