Diabetes insipidus - nephrogenic - Symptom
Nephrogenic diabetes insipidus; Acquired nephrogenic diabetes insipidus; Congenital diabetes insipidus
You may have intense or uncontrollable thirst, and crave ice water. You will produce large amounts of urine, usually more than 3 - 15 liters per day.
If you do not drink enough fluids, dehydration can result. Symptoms may include:
- Dry mucous membranes
- Dry skin
- Sunken appearance to eyes
- Sunken fontanelles (soft spot) in infants
Other symptoms that can occur due to inadequate fluids include:
Signs and tests:
A physical exam may reveal:
- Low blood pressure
- Rapid pulse
- Signs of dehydration
Testing may reveal:
- High serum osmolality
- High urine output, regardless of how many fluids you drink
- Kidneys don't concentrate urine when the person is given ADH
- Low urine osmolality
- Normal or high ADH levels
Other tests that may be done include:
- Reviewed last on: 6/1/2010
- Charles Silberberg, DO, Private Practice specializing in Nephrology, Affiliated with New York Medical College, Division of Nephrology, Valhalla, NY. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
Verbalis JG. Posterior pituitary. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 243.
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