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Renal cell carcinoma - Overview

Alternative Names

Renal cancer; Kidney cancer; Hypernephroma; Adenocarcinoma of renal cells; Cancer - kidney

Definition of Renal cell carcinoma:

Renal cell carcinoma is a type of kidney cancer in which the cancerous cells are found in the lining of very small tubes (tubules) in the kidney.

Causes, incidence, and risk factors:

Renal cell carcinoma is the most common type of kidney cancer in adults. It occurs most often in men ages 50-70.

The exact cause is unknown.

Risk factors include:

  • Dialysis treatment
  • Family history of the disease
  • Genetics
  • Smoking
  • Von Hippel-Lindau disease (a hereditary disease that affects the capillaries of the brain, eyes, and other body parts)
  • Reviewed last on: 2/12/2009
  • David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Barjorin D. Tumors of the kidney, bladder, ureters, and renal pelvis. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007: chap 2007.

National Comprehensive Cancer Network Clinical Practice Guidelines in Oncology: Kidney Cancer. National Comprehensive Cancer Network; 2009. Version 1.2009.

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