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Hereditary spherocytosis; Spherocytosis
Surgery to remove the spleen (splenectomy) cures the anemia but doesn't correct the abnormal cell shape.
Families with a history of spherocytosis should have their children screened for this disorder.
Children should wait until age 5 to have splenectomy because of the infection risk. In mild cases discovered in adults, it may not be necessary to remove the spleen.
Children and adults should be given a pneumococcal vaccine before spleen removal surgery, and also may receive folic acid supplements. Additional vaccines may be indicated based on the patient' s history.
This outcome is usually good with treatment. After the spleen is removed, the life span of the red blood cell returns to normal.
Call your health care provider for an appointment if your symptoms get worse, do not improve with treatment, or if you develop new symptoms.
Golan DE. Hemolytic anemias: red cell membrane and metabolic disorders. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 165.
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