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Primary amyloidosis - Symptom

Alternative Names

Amyloid - primary

Symptoms:

  • Enlarged tongue
  • Fatigue
  • Irregular heart rhythm
  • Numbness of hands and feet
  • Shortness of breath
  • Skin changes
  • Swallowing difficulties
  • Swelling in the arms and legs
  • Weak hand grip
  • Weight loss

Additional symptoms that may be associated with this disease:

Signs and tests:

Your doctor may discover that you have an enlarged liver or spleen. You may also have signs of heart failure.

If specific organ damage is suspected, your doctor may order tests to confirm amyloidosis of that organ. For example:

This disease may also alter the results of the following tests:

  • Reviewed last on: 2/26/2007
  • William Matsui, MD, Assistant Professor of Oncology, Division of Hematologic Malignancies, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD. Review provided by VeriMed Healthcare Network.

References

Buxbaum JN. The Amyloidoses. In: Goldman L, Ausiello D. Cecil Textbook of Medicine. 22nd ed. Philadelphia, Pa: WB Saunders; 2004.

Hoffman R, Benz Jr. EJ, Shattil SJ, et al., eds. Hematology: Basic Principles and Practice. 4th ed. Philladelphia, Pa: Churchill Livingston; 2005:1540-48.