Extrinsic factor deficiency
Patients can control bleeding episodes with normal plasma, concentrates of factor VII, or genetically produced (recombinant) factor VII. People need frequent treatment during bleeding episodes because factor VII does not last for long. Women can control menstrual bleeding with oral contraceptives. An activated concentrate of factor VII called Novo-7 can also be used.
The stress of illness can often be helped by joining a support group where members share common experiences and problems. See hemophilia - resources.
The outcome can be good with proper treatment.
Go to the emergency room or call the local emergency number (such as 911) if you have severe, unexplained bleeding.
Hoffman R, Benz E, Shattil S, Furie B, Cohen H. Hematology: Basic Principles and Practice. 4th ed. Philadelphia, Pa: Churchill Livingstone; 2004.
Levi M, Peters M, Büller HR. Efficacy and safety of recombinant factor VIIa for treatment of severe bleeding: A systematic review. Crit Care Med. April 2005;33:883-890.