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Factor VII deficiency - Treatment

Alternative Names

Extrinsic factor deficiency

Treatment:

Patients can control bleeding episodes with normal plasma, concentrates of factor VII, or genetically produced (recombinant) factor VII. People need frequent treatment during bleeding episodes because factor VII does not last for long. Women can control menstrual bleeding with oral contraceptives. An activated concentrate of factor VII called Novo-7 can also be used.

Support Groups:

The stress of illness can often be helped by joining a support group where members share common experiences and problems. See hemophilia - resources.

Expectations (prognosis):

The outcome can be good with proper treatment.

Complications:

  • Hemorrhage
  • Stroke or other nervous system problems from central nervous system bleeding
  • Joint problems in severe cases when bleeding happens often

Calling your health care provider:

Go to the emergency room or call the local emergency number (such as 911) if you have severe, unexplained bleeding.

  • Reviewed last on: 3/13/2007
  • Mark Levin, MD, Hematologist and Oncologist, Newark, NJ. Review provided by VeriMed Healthcare Network.

References

Hoffman R, Benz E, Shattil S, Furie B, Cohen H. Hematology: Basic Principles and Practice. 4th ed. Philadelphia, Pa: Churchill Livingstone; 2004.

Levi M, Peters M, Büller HR. Efficacy and safety of recombinant factor VIIa for treatment of severe bleeding: A systematic review. Crit Care Med. April 2005;33:883-890.