Factor VII deficiency - Treatment
Extrinsic factor deficiency
Patients can control bleeding episodes by receiving normal plasma, concentrates of factor VII, or genetically produced (recombinant) factor VII through a vein (intravenous). People need frequent treatment during bleeding episodes because factor VII does not last for long inside the body. A form of factor VII called NovoSeven can also be used.
If a lack of vitamin K is causing the disorder, you can take vitamin K by mouth, through injections under the skin, or through a vein (intravenously).
You can often help the stress of illness by joining a support group where members share common experiences and problems. See hemophilia - resources.
The outcome can be good with proper treatment.
This is a life-long disorder if you get it from your parents. If it is caused by liver disease, the outcome depends on how well your liver problem can be treated.
- Excessive bleeding (hemorrhage)
- Stroke or other nervous system problems from central nervous system bleeding
- Joint problems in severe cases when bleeding happens often
Calling your health care provider:
Go to the emergency room or call the local emergency number (such as 911) if you have severe, unexplained bleeding.
- Reviewed last on: 2/28/2011
- David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
Gailani d, Neff AT. Rare coagulation factor deficiencies. In: Hoffman R, Benz EJ Jr, Shattil SJ, et al, eds. Hoffman Hematology: Basic Principles and Practice. 5th ed. Philadelphia, Pa: Churchill Livingstone Elsevier;2008:chap 127.
Kessler C. Hemorrhagic disorders: coagulation factor deficiencies. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa:Saunders Elsevier;2007:chap 180.
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