The goal is to identify and treat the cause of the folate deficiency.
Folic acid supplements may be given by mouth (oral) or through a vein (intravenous) on a short-term basis until the anemia has been corrected. In the case of poor absorption by the intestine -- replacement therapy may be lifelong.
Dietary treatment consists of increasing the intake of green, leafy vegetables and citrus fruits.
Anemia usually responds well to treatment within 2 months.
Symptoms of anemia can cause discomfort. In pregnant women, folate deficiency has been associated with neural tube or spinal defects (such as spina bifida) in the infant.
Other, more severe complications may include:
Call for an appointment with your health care provider if you have symptoms of folate deficiency anemia.
Antony AC. Megoblastic anemias. In: Hoffman R, Benz EJ, Shattil SS, et al., eds. Hematology: Basic Principles and Practice. 5th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2008:chap 39.
Kaferie J, Strzoda CE. Evaluation of macrocytosis. Am Fam Physician. 2009;79:203-208.
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