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Thrombotic thrombocytopenic purpura - Symptom
Alternative Names
TTP
Symptoms:
- Fever
- Weakness
- Easy fatigue
- Pallor
- Shortness of breath on exertion
- Heart rate over 100 beats per minute
- Purplish spots in the skin produced by small bleeding vessels near the surface of the skin (purpura)
- Bleeding into the skin or mucus membranes
- Headache
- Confusion
- Speech changes
- Changes in consciousness
- Yellowish color to the skin (jaundice)
Signs and tests:
- Platelet count is low
- CBC shows anemia
- Bilirubin is high
- Blood smear shows broken red blood cells (schistocytes) and fragmented blood cells
- Urinalysis shows protein or very tiny blood particles
- Creatinine level is high
- Mucus membrane biopsy shows platelet clots in small blood vessels
- Reviewed last on: 4/27/2007
- Rita Nanda, M.D., Department of Medicine, Section of Hematology/Oncology, University of Chicago Medical Center, Chicago, IL. Review provided by VeriMed Healthcare Network.
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