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Factor X deficiency - Treatment

Alternative Names

Stuart-Prower deficiency

Treatment:

Treatment for the bleeding disorder is to get fresh frozen plasma or factor X concentrates into the blood during sudden (acute) episodes or before surgery. If the disorder is caused by amyloidosis, surgery is done to remove the spleen.

Support Groups:

You can ease the stress of illness by joining a support group where members share common experiences and problems. See hemophilia - resources.

Expectations (prognosis):

The outcome is usually good with mild disease or treatment.

Complications:

Severe bleeding or sudden loss of blood (hemorrhage) can occur. The joints may get deformed in severe disease from many bleeds.

Calling your health care provider:

Call your health care provider, go to the emergency room, or call the local emergency number (such as 911) if you have an unexplained or severe loss of blood.

  • Reviewed last on: 3/13/2007
  • Mark Levin, MD, Hematologist and Oncologist, Newark, NJ. Review provided by VeriMed Healthcare Network.

References

Hoffman R, Benz E, Shattil S, Furie B, Cohen H. Hematology: Basic Principles and Practice. 4th ed. Philadelphia, Pa: Churchill Livingstone; 2004.

Sucker C, Hetzel GR, Grabensee B, Stockschlaeder M, Scharf RE. Amyloidosis and Bleeding: Pathophysiology, Diagnosis, and Therapy. Am J Kidney Dis. June 2006;47:947-955.

Takabe K, Holman PR, Herbst KD, Glass CA, Bouvet M. Successful perioperative management of factor X deficiency associated with primary amyloidosis. J Gastrointest Surg. March 2004;8:358-362.