Definition of Drug-induced nonimmune thrombocytopenia:

Drug-induced nonimmune thrombocytopenia is a condition in which certain drugs reduce the number of normal clot-forming blood cells (platelets).

Causes, incidence, and risk factors:

Platelets are important in forming blood clots. Certain drugs may decrease the number of platelets by damaging the bone marrow where platelets are made. Decreased platelets may cause easy bruising or abnormal bleeding.

Bleeding can be life-threatening if it occurs in the brain or other vital organs. Other drugs (such as aspirin) can increase the risk of bleeding by stopping platelets from working normally.