Protein S deficiency; Protein C deficiency
Blood-thinning drugs (heparin and warfarin) are used to treat and prevent blood clots.
The outcome is usually good with treatment, but symptoms may return.
In rare cases, using warfarin to thin the blood and prevent clots can cause brief increased clotting and severe skin wounds. Patients are at risk if they are not treated with the blood-thinning drug heparin before taking warfarin.
Call your health care provider if you have symptoms of clotting in a vein (such as swelling and redness of the leg).
Schafer AI. Thrombotic disorders: hypercoagulable states. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 182.