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Anemia - B12 deficiency - Treatment

Alternative Names

Macrocytic anemia

Treatment:

Treatment depends on the specific cause of B12 deficiency anemia.

Pernicious anemia requires lifelong vitamin B12 injections. People with anemia due to a lack of dietary vitamin B12 may be told to take vitamin supplements and follow a more balanced diet. Treatment may start with vitamin B12 injections.

Anemia caused by malabsorption is treated with vitamin B12 injections until the condition improves.

Expectations (prognosis):

Treatment for this form of anemia is usually effective.

Complications:

  • The signs and symptoms related to the central nervous system may be irreversible if treatment is not begun within 6 months of when these symptoms begin.
  • Vitamin B12 affects cells that form the outer surface of the body and line inner passageways (epithelial cells). Therefore, a lack of B12 may cause a falsely abnormal Pap smear.

Calling your health care provider:

Call your health care provider if you have any of the symptoms of anemia.

  • Reviewed last on: 11/23/2008
  • David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Antony AC. Megaloblastic anemias. Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007: chap 170.

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