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HIV infection - Overview

Alternative Names

Human immunodeficiency virus infection

Definition of HIV infection:

HIV infection is a condition caused by the human immunodeficiency virus (HIV). The condition gradually destroys the immune system, which makes it harder for the body to fight infections.

This article provides a general overview. For more detailed information, see:

Causes, incidence, and risk factors:

The human immunodeficiency virus (HIV) can be spread by the following:

  • Through sexual contact -- including oral, vaginal, and anal sex
  • Through blood -- through blood transfusions, accidental needlesticks, or needle sharing
  • From mother to child -- a pregnant woman can transmit the virus to her fetus through their shared blood circulation, or a nursing mother can pass it to her baby in her breast milk

People who become infected with HIV may have no symptoms for up to 10 years, but they can still pass the infection to others. After being exposed to the virus, it can take up to 3 months for the HIV ELISA blood test to change from HIV negative to HIV positive.

HIV has spread throughout the U.S. The disease is more common in urban areas, especially in inner cities.

See also: AIDS for a more complete description of how HIV is spread.

  • Reviewed last on: 6/9/2011
  • David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; Jatin M. Vyas, MD, PhD, Assistant Professor in Medicine, Harvard Medical School; Assistant in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Piot P. Human immunodeficiency virus infection and acquired immunodeficiency syndrome: A global overview. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier;2007:chap 407.

Del Rio C, Curran JW. Epidemiology and prevention of acquired immunodeficiency syndrome and human immunodeficiency virus infection. In: Mandell GL, Bennett JE, Dolin R, eds. Principles and Practice of Infectious Diseases. 7th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2009:chap 118.

Sterling TR, Chaisson RE. General clinical manifestations of human immunodeficiency virus infection (including the acute retroviral syndrome and oral, cutaenous, renal, ocular, metabolic, and cardiac diseases. In: Mandell GL, Bennett JE, Dolin R, eds. Principles and Practice of Infectious Diseases. 7th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2009:chap 121.

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