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Herpes labialis - Treatment

Alternative Names

Cold sore; Fever blister; Herpes simplex - oral; Oral herpes simplex

Treatment:

Untreated, the symptoms will generally go away in 1 to 2 weeks. Antiviral medications taken by mouth may shorten the course of the symptoms and decrease pain.

Herpes sores often come back again and again. The antiviral medicines work best if you take them when the virus is just starting to come back -- before you see any sores. If the virus returns frequently, your doctor may recommend that you take the medicines all the time.

Wash blisters gently with soap and water to reduce the spread of the virus to other areas of skin. An antiseptic soap may be recommended. Applying ice or warmth to the area may reduce pain.

Expectations (prognosis):

Herpes labialis usually disappears spontaneously in 1 to 2 weeks. It may recur. Infection may be severe and dangerous if it occurs in or near the eye, or if it happens in immunosuppressed people.

Complications:

  • Spread of herpes to other skin areas
  • Secondary bacterial skin infections
  • Recurrence of herpes labialis
  • Generalized infection -- may be life-threatening in immunosuppressed people, including those with atopic dermatitis, cancer, or HIV infections
  • Blindness

Herpes infection of the eye is a leading cause of blindness in the US, causing scarring of the cornea.

Calling your health care provider:

Call for an appointment with your health care provider if symptoms indicate herpes labialis and symptoms persist for more than 1 or 2 weeks.

Call if symptoms are severe, or if you have a disorder associated with immunosuppression and you develop herpes symptoms.

  • Reviewed last on: 5/21/2008
  • D. Scott Smith, M.D., MSc, DTM&H, Chief of Infectious Disease & Geographic Medicine, Kaiser Redwood City, CA & Adjunct Assistant Professor, Stanford University.  Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Gonsalves WC. Common oral lesions: Part I. Superficial mucosal lesions. Am Fam Physician. Feb 2007; 75(4): 501-7.

Fatahzadeh M. Human herpes simplex virus infections: epidemiology, pathogenesis, symptomatology, diagnosis, and management. J Am Acad Dermatol. Nov. 2007; 57(5): 737-63.