Staphylococcal meningitis is a bacterial infection of the membranes covering the brain and spinal cord (meninges).
Staphylococcal meningitis is caused by Staphylococcus bacteria. When it is caused by Staphylococcus aureus or Staphylococcus epidermidis bacteria, it usually develops as a complication of a surgical procedure, or as an infection spread by the blood from another site.
Risk factors include:
Symptoms usually come on quickly, and may include:
Other symptoms that can occur with this disease:
Physical examination will usually show:
For any patient who is suspected of having meningitis, it is important to perform a lumbar puncture ("spinal tap"), in which spinal fluid (known as cerebrospinal fluid, or CSF) is collected for testing.
Tests may include:
Treatment with antibiotics should be started as soon as possible. Ceftriaxone is one of the most commonly used antibiotics. Nafcillin is also an effective treatment for staphylococcal meningitis.
If the antibiotic is not working and the health care provider suspects antibiotic resistance, vancomycin may be used.
Often, treatment will include a search for, and removal of, possible sources of bacteria in the body. These include shunts or artificial heart valves.
Early treatment improves the outcome. However, 3 - 5% of patients do not survive. Young children and adults over age 50 have the highest risk of death.
Staphylococcal meningitis often improves more quickly, with better results, if the source of the infection is removed. The source may include shunts, hardware in joints, or artificial heart valves.
Call the local emergency number (such as 911) or go to an emergency room if you suspect meningitis in a young child who has the following symptoms:
Call the local emergency number if you develop any of the serious symptoms listed above. Meningitis can quickly become a life-threatening illness.
In high-risk people, taking preventive antibiotics before diagnostic or surgical procedures may help reduce the risk. Discuss this with your doctor.
Swartz MN. Meningitis: bacterial, viral, and other. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007: chap 437.
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