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Gas gangrene - Treatment

Alternative Names

Tissue infection - Clostridial; Gangrene - gas; Myonecrosis; Clostridial infection of tissues

Treatment:

The person will need to have surgery quickly to remove dead, damaged, and infected tissue (debridement). Surgical removal (amputation) of an arm or leg may be needed to control the spread of infection. Often this must occur before all diagnostic test results are available.

Patients should get antibiotics, preferably penicillin-type with clindamycin. Initially, patients receive antibiotics through a vein (intravenously). Some people may need analgesics to control pain. Doctors have tried hyperbaric oxygen for this condition, with varying degrees of success.

Expectations (prognosis):

Gas gangrene is progressive and often fatal.

Complications:

  • Coma
  • Delirium
  • Disfiguring or disabling permanent tissue damage
  • Jaundice with liver damage
  • Kidney failure
  • Shock
  • Spread of infection through the body (sepsis)
  • Stupor

Calling your health care provider:

This is an emergency condition requiring immediate medical attention.

Call your heath care provider if you have signs of infection around a skin wound. Go to the emergency room or call the local emergency number (such as 911), if you have symptoms of gas gangrene.

  • Reviewed last on: 12/1/2009
  • David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; Jatin M. Vyas, MD, PhD, Assistant Professor in Medicine, Harvard Medical School, Assistant in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Bartlett JG. Clostridial infections. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 319.

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