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Lyme disease - early disseminated - Symptom

Alternative Names

Lyme disease - secondary or stage 2; Stage 2 Lyme disease, Bannwarth syndrome

Symptoms:

Some patients will remember having a tick bite or symptoms of stage 1 Lyme disease. Some patients with early disseminated or secondary Lyme disease may not have any history of symptoms, tick bites, or skin rashes.

Lyme disease can affect the central nervous system and cardiac system. Symptoms can come and go and may disappear after days, weeks, or months.

Symptoms include:

Other symptoms that can occur with this disease:

Signs and tests:

A physical examination may show signs of neurological problems or heart involvement.

Tests that may be done include:

  • Chest x-ray
  • ECG
  • ELISA test to screen for substances specific to the infection
  • Examination of cerebrospinal (CSF) fluid
  • Western blot to confirm the presence of antibodies to Borrelia burgdorferi
  • Reviewed last on: 5/20/2008
  • Jatin M. Vyas, PHD, MD, Instructor in Medicine, Harvard Medical School, Assistant in Medicine, Division of Infectious Disease, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Wormser GP, Dattwyler RJ, Shapiro ED, Halperin JJ, Steere AC, Klempner MS, et al. The clinical assessment, treatment, and prevention of Lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the Infectious Diseases Society of America. Clin Infect Dis. 2006;43:1089-1134.

Feder HM Jr, Johnson BJ, O'Connell S, Shapiro ED, Steere AC, Wormser GP; Ad Hoc International Lyme Disease Group. A critical appraisal of "chronic Lyme disease." N Engl J Med. 2007 Oct 4;357(14):1422-30.

Halperin JJ, Shapiro ED, Logigian E, Belman AL, Dotevall L, Wormser GP, et al. Practice parameter: treatment of nervous system Lyme disease (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 2007 Jul 3;69(1):91-102. Epub 2007 May 23.

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