There are two goals in treating a sexually transmitted disease, especially one as easily spread as gonorrhea. The first is to cure the infection in the patient. The second is to locate and test all of the other people the person had sexual contact with and treat them to prevent further spread of the disease.
Penicillin used to be given to patients with gonorrhea. But it is not often used anymore because some types of the gonorrhea bacteria no longer respond to the drug. This is called antibiotic resistance. Antibiotic resistance is major public health threat in which bacteria cannot be killed with the usual antibiotic medicines.
The bacteria responsible for gonorrhea is growing increasingly resistant to another class of antibiotics called fluoroquinolones, which includes ciprofloxacin, ofloxacin, or levofloxacin. The U.S. Centers for Disease Control and Prevention now recommendeds against using these medicines to treat gonorrhea.
Gonorrhea is now treated with potent antibiotics called cephalosporins, including ceftriaxone (Rocephin). For gonococcemia, treatment is usually first given through an IV rather than by mouth. Since chlamydia frequently occurs along with gonorrhea, treatment for chlamydia is often given at the same time.
A follow-up visit after treatment is important to recheck lab tests and make sure the infection is cured.
With proper treatment, the outcome is expected to be good. When treatment is delayed there is a greater chance of complications.
Call your health care provider if you have symptoms of disseminated gonococcemia.
Centers for Disease Control and Prevention (CDC). Update to CDC's Sexually Transmitted Diseases Treatment Guidelines, 2006: Fluoroquinolones No Longer Recommended for Treatment of Gonococcal Infections. MMWR . 2007; 56(14);332-336.
U.S. Preventive Services Task Force. Screening for Gonorrhea: Recommendation Statement. Am Fam Physician . Nov. 1, 2005; 72(9); 1783-1786.
Cohen J, Powderly WG. Infectious Diseases . 2nd ed. New York, NY: Elsevier; 2004:2173-2186.
Centers for Disease Control and Prevention. Sexually Transmitted Disease Surveillance, 2004. Atlanta, GA: U.S. Department of Health and Human Service, September 2005.
Weinstock H, Berman S, Cates W. Sexually transmitted disease among American youth: Incidence and prevalence estimates, 2000. Perspect Sex Reprod Health . 2004; 36: 6-10.
Centers for Disease Control and Prevention. Sexually Transmitted Diseases Treatment Guidelines 2002. MMWR . 2002;51(no. RR-6).
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