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Toxic shock syndrome - Overview

Alternative Names

Staphylococcal toxic shock syndrome

Definition of Toxic shock syndrome:

Toxic shock syndrome is a severe disease that involves fever, shock, and problems with the function of several body organs.

Causes, incidence, and risk factors:

Toxic shock syndrome is caused by a toxin produced by certain types of Staphylococcus bacteria. A similar syndrome, called toxic shock-like syndrome (TSLS), can be caused by Streptococcal bacteria.

Although the earliest described cases of toxic shock syndrome involved women who were using tampons during their periods (menstruation), just slightly over half of current cases are associated with such events. Toxic shock syndrome can also occur in children, postmenopausal women, and men.

Risk factors include:

  • Childbirth
  • Current Staphylococcus aureus (S. aureus) infection
  • Foreign bodies or packings (such as those used to stop nosebleeds)
  • Menstruation
  • Surgery
  • Tampon use (particularly if you leave on in for a long time)
  • Use of barrier contraceptives such as a diaphragm or vaginal sponge
  • Reviewed last on: 9/3/2008
  • D. Scott Smith, M.D., MSc, DTM&H, Chief of Infectious Disease & Geographic Medicine, Kaiser Redwood City, CA & Adjunct Assistant Professor, Stanford University.  Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Hans D, Kelly E, Wilhelmson K, Katz ED. Rapidly Fatal Infections. Emerg Med Clin North Am. 2008 May;26(2):259-79, vii.

Todd JK. Toxic Shock Syndrome. In: Long SS, Pickering LK, Prober CG, eds. Principles and Practice of Pediatric Infectious Diseases. 2nd ed. Philadelphia, Pa: Churchill Livingstone; 2003:chap 13.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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