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Tardive dyskinesia

• Overview
• Symptoms

Definition:

Tardive dyskinesia is a disorder that causes involuntary movements (especially of the lower face).

Causes, incidence, and risk factors:

Tardive dyskinesia is serious side effect of long-term use of drugs called neuroleptics. The most commonly used neuroleptics are older anti-psychotic drugs, including haloperidol, trifluoperazine, or fluphenazine.

References:

Nasrallah HA. Focus on lower risk of tardive dyskinesia with atypical antipsychotics. Ann Clin Psychiatry . 2006 Jan-Mar;18(1):57-62.

Chen JJ, Lee KC. Nonparkinsonism movement disorders in the elderly. Consult Pharm . 2006 Jan;21(1):58-71.

Margolese HC, Chouinard G, Kolivakis TT, Beauclair L, Miller R. Tardive dyskinesia in the era of typical and atypical antipsychotics. Part 1: pathophysiology and mechanisms of induction. Can J Psychiatry . 2005 Aug;50(9):541-7. Review.

• Review Date: 4/28/2006
• Reviewed By: Daniel Kantor, M.D., Director of the Comprehensive MS Center, Neuroscience Institute, University of Florida Health Science Center, Jacksonville, FL. Review provided by VeriMed Healthcare Network.

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