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Lobar intracerebral hemorrhage

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Definition:

Lobar intracerebral hemorrhage is bleeding in the largest part of the brain called the cerebrum.

Alternative Names:

Hemorrhage - intraparenchymal; Hemorrhage - intracerebral (lobar)

Causes, incidence, and risk factors:

Lobar intracerebral hemorrhage (ICH) may be caused by traumatic brain injury or blood vessel problems, such as aneurysm , arteriovenous malformation , or angioma, a type of blood vessel tumor.

When it is not caused by trauma, lobar intracerebral hemorrhage is considered a type of hemorrhagic stroke , the most serious type of stroke.

Lobar ICH is associated with the apolipoprotein (apo) E gene, which is linked to an increased risk for Alzheimer's disease.

Lobar hemorrhages are also associated with the following:

• Various blood or bleeding disorders , such as disseminated intravascular coagulation , hemophilia , sickle cell anemia , and leukemia.
• Decreased levels of blood platelets
• Use of aspirin or blood thinners
• Liver disease (associated with increased bleeding risk)
• Cerebral amyloid
• Some autoimmune disorders

References:

Woo D, Kaushal R, Chakraborty R, et. al. Association of apolipoprotein E4 and haplotypes of the apolipoprotein E gene with lobar intracerebral hemorrhage. Stroke . 2005 Sep;36(9):1874-9.

• Review Date: 7/14/2006
• Reviewed By: J.A. Lee, M.D., Division of Surgery, UCSF, San Francisco, CA. Review provided by VeriMed Healthcare Network.

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