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Progressive neuropathic (peroneal) muscular atrophy; Hereditary peroneal nerve dysfunction; Neuropathy - peroneal (hereditary); Hereditary motor and sensory neuropathy
Nerves that stimulate movement (called the motor nerves) are most severely affected. The nerves in the legs are affected first and most severely.
Symptoms usually begin between mid-childhood and early adulthood. They may include:
Later, similar symptoms may appear in the arms and hands, which may include a claw-like hand.
A physical exam may show:
A muscle biopsy or nerve biopsy may confirm the diagnosis. Nerve conduction tests are often done to tell the difference between different forms of the disorder.
Genetic testing is available for most forms of the disease.
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