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Stroke secondary to atherosclerosis

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Definition:

Stroke secondary to atherosclerosis refers to loss of neurologic functions (brain attack), which occurs because of atherosclerosis .

Causes, incidence, and risk factors:

Stroke secondary to atherosclerosis affects about 2 out of 1,000 people, or approximately 50% of all those who have strokes.

Atherosclerosis ( hardening of the arteries ) occurs when sticky, fatty substances called plaque build up in the inner lining of the arteries. The plaque may slowly block or narrow an artery or trigger a clot ( thrombus ). Clots can lead to stroke.

Risks for stroke secondary to atherosclerosis include:

• History of high blood pressure ( hypertension )
• Peripheral vascular disease
• Smoking
• Transient ischemic attacks or other cerebrovascular disease
• High cholesterol
• High levels of homocysteine
• Diabetes
• Obesity
• Sedentary lifestyle
• Kidney disease requiring dialysis

References:

Mosca L, Banka CL, Benjamin EJ, et al. Evidence-Based Guidelines for Cardiovascular Disease Prevention in Women: 2007 Update. Circulation . 2007; Published online before print February 19, 2007.

• Review Date: 2/20/2007
• Reviewed By: Updated by: A.D.A.M. Editorial Team: Greg Juhn, M.T.P.W., David R. Eltz, Kelli A. Stacy. Previously reviewed by Daniel Kantor, M.D., Director of the Comprehensive MS Center, Neuroscience Institute, University of Florida Health Science Center, Jacksonville, FL. Review provided by VeriMed Healthcare Network. (April 2006)

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