Definition of Stroke related to cocaine use:

Stroke related to cocaine use is a blockage in the blood supply to the brain and loss of brain function in someone who has used the drug, cocaine.

Causes, incidence, and risk factors:

Cocaine is a product of the coca plant and an illegal recreational drug. It is a strong stimulant that increases activity of the central nervous system and the nerves that run away from the spinal cord (peripheral nervous system).

Cocaine use can cause a number of medical problems. Stroke related to cocaine probably occurs because cocaine causes blood vessels to narrow (constrict) while it increases blood pressure (hypertension). This vasoconstriction can be severe enough to reduce or block blood flow through the arteries in the brain. Cocaine use also can lead to swelling (inflammation) of the arteries of the brain.

Stroke related to cocaine is most common in men under 40 years old. A history of recent cocaine use is a risk.

A few people who experience stroke after using cocaine have an arteriovenous malformation, which may make them more likely to have a stroke. In these cases the stroke is due to bleeding in the brain instead of decreased blood flow.