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General paresis - Treatment

Treatment:

The goals of treatment are to cure the infection and slow the disorder from getting worse. The doctor will prescribe penicillin or other antibiotics, such as doxycycline, to treat the infection. Treatment may continue until the infection has completely cleared.

Treating the infection will reduce new nerve damage, but it will not cure damage that has already occurred. A follow-up examination of the cerebrospinal fluid is needed to see whether the antibiotic therapy worked.

Treatment of symptoms is needed for existing nervous system damage. Emergency treatment of seizures may be needed. Anticonvulsants (such as phenytoin) can help control seizures.

Patients who are unable to care for themselves may need help with such activities as eating and dressing. Those with muscle weakness may need occupational therapy or physical therapy.

Expectations (prognosis):

Without treatment, people can become disabled. People with late syphilis infections are more likely to get other infections and diseases.

Complications:

  • Inability to care for yourself
  • Inability to communicate or interact with others
  • Injury due to seizures or falls

Calling your health care provider:

Call your health care provider if you have symptoms of general paresis, especially if you know you've been infected with syphilis.

Go to the emergency room or call the local emergency number (such as 911) if you have seizures.

  • Reviewed last on: 2/13/2008
  • Luc Jasmin, MD, PhD, Departments of Anatomy & Neurological Surgery, University of California, San Francisco, CA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Moore DP, Jefferson JW. Handbook of Medical Psychiatry. 2nd ed. St. Louis, Mo: Mosby; 2004:404-406.

Goetz, CG. Textbook of Clinical Neurology. 2nd ed. St. Louis, Mo: WB Saunders; 2003: 931-933.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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