Parkinson's disease - Symptom
Alternative Names
Paralysis agitans; Shaking palsy
Symptoms:
- Muscle rigidity
- Stiffness
- Difficulty bending arms or legs
- Unstable, stooped, or slumped-over posture
- Loss of balance
- Gait (walking pattern) changes
- Shuffling walk
- Slow movements
- Difficulty initiating any voluntary movement
- Difficulty beginning to walk
- Difficulty getting up from a chair
- Small steps followed by the need to run to maintain balance
- Freezing of movement when the movement is stopped, inability to resume movement
- Muscle aches and pains (myalgia)
- Shaking, tremors (varying degrees, may not be present)
- Characteristically occur at rest, may occur at any time
- May become severe enough to interfere with activities
- May be worse when tired, excited, or stressed
- Finger-thumb rubbing (pill-rolling tremor) may be present
- Changes in facial expression
- Reduced ability to show facial expressions
- "Mask" appearance to face
- Staring
- May be unable to close mouth
- Reduced rate of blinking
- Voice or speech changes
- Loss of fine motor skills
- Frequent falls
- Decline in intellectual function (may occur, can be severe)
- A variety of gastrointestinal symptoms, mainly constipation.
Note: Initial symptoms may be mild and nonspecific. For instance, the patient may have a mild tremor or a slight feeling that one leg or foot is stiff and dragging.
Additional symptoms that may be associated with this disease:
Signs and tests:
The health care provider may be able to diagnose Parkinson's disease based on your symptoms and physical examination. However, the symptoms may be difficult to assess, particularly in the elderly. For example, the tremor may not appear when the person is sitting quietly with arms in the lap. The posture changes may be similar to osteoporosis or other changes associated with aging. Lack of facial expression may be a sign of depression.
An examination may show jerky, stiff movements, tremors of the Parkinson's type, and difficulty starting or completing voluntary movements. Reflexes are essentially normal.
Tests may be needed to rule out other disorders that cause similar symptoms.
See also: Essential tremor
- Reviewed last on: 5/10/2007
- A.D.A.M. Editorial Team: Greg Juhn, M.T.P.W., David R. Eltz, Kelli A. Stacy. Previously reviewed by Daniel Kantor, M.D., Director of the Comprehensive MS Center, Neuroscience Institute, University of Florida Health Science Center, Jacksonville, FL. Review provided by VeriMed Healthcare Network (5/242006).
References
U.S. Food and Drug Administration. FDA Approves Neupro Patch for Treatment of Early Parkinson's Disease. Rockville, MD: National Press Office; May 9, 2007. Release P07-84.
Goetz, CG. Textbook of Clinical Neurology. 2nd ed. St. Louis, Mo: WB Saunders; 2003: 713-720.
Noble J. Textbook of Primary Care Medicine. 3rd ed. St. Louis, Mo: Mosby; 2001:1612-1618.