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Brain tumor - children - Overview

Alternative Names

Glioblastoma multiforme - children; Ependymoma - children; Glioma - children; Astrocytoma - children; Medulloblastoma - children; Neuroglioma - children; Oligodendroglioma - children; Meningioma - children; Cancer - brain tumor (children)

Definition of Brain tumor - children:

A primary brain tumor is a group (mass) of abnormal cells that start in the brain. This article focuses on primary brain tumors in children.

Causes, incidence, and risk factors:

The cause of primary brain tumors is unknown. Primary brain tumors may be:

  • Not cancerous (benign)
  • Invasive (spread to nearby areas)
  • Located in only a small area
  • Cancerous (malignant)

Brain tumors are classified depending on:

  • The exact site of the tumor
  • The type of tissue involved
  • Whether it is cancerous

Brain tumors can directly destroy brain cells. They may also indirectly damage cells by pushing on other parts of the brain. This leads to swelling and increased pressure within the skull.

Tumors may occur at any age, but many tumors are more common at a certain age. However, most brain tumors are rare in the first year of life.

COMMON TUMOR TYPES

Astrocytomas are usually noncancerous, slow-growing cysts. They most commonly develop in children ages 5 - 8.

Brainstem gliomas occur almost only in children. The average age at which they develop is about 6 years old. The tumor may grow very large before causing symptoms.

Ependymomas are located in tiny passageways (ventricles) in the brain, and block the flow of cerebrospinal fluid (CSF).

Medulloblastomas are the most common type of childhood brain cancer. They occur more often in boys than girls, usually around age 5. Most medulloblastomas occur before age 10.

  • Reviewed last on: 12/28/2010
  • Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Buckner JC, Brown PD, O'Neill BP, Meyer FB, Wetmore CJ, Uhm JH. Central nervous system tumors. Mayo Clin Proc. 2007;82(10):1271-1286.

National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology: Central nervous system cancers. V.2.2009.

Wilne S, Koller K, Collier J, Kennedy C, Grundy R, Walker D. The diagnosis of brain tumours in children: a guideline to assist healthcare professionals in the assessment of children who may have a brain tumour. Arch Dis Child. 2010;95:534-539.

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