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Brain tumor - metastatic (secondary); Cancer - brain tumor (metastatic)
Treatment depends on the size and type of the tumor, the initial site of the tumor, and the general health of the person. The goals of treatment may be relief of symptoms, improved functioning, or comfort.
Radiation to the whole brain is often used to treat tumors that have spread to the brain, especially if there is more than one tumor.
Surgery may be used for metastatic brain tumors when there is a single lesion and when there is no cancer elsewhere in the body. Some may be completely removed. Tumors that are deep or that infiltrate brain tissue may be debulked (removing much of the tumor's mass to reduce its size).
Surgery may reduce pressure and relieve symptoms in cases when the tumor cannot be removed.
Chemotherapy for brain metastases is not as helpful as surgery or radiation for many types of cancer.
Stereotactic radiosurgery is used at some hospitals. This is a form of radiation therapy that focuses high-powered x-rays on a small area of the brain.
Medications for some symptoms of a brain tumor may include the following:
When widespread cancer is discovered, treatment may focus primarily on relief of pain and other symptoms. This is called palliative or supportive care.
Comfort measures, safety measures, physical therapy, occupational therapy, and other interventions may improve the patient's quality of life. Legal advice may be helpful in forming advanced directives, such as power of attorney, in cases where continued physical or intellectual decline is likely.
For additional information, see cancer resources.
In general, the probable outcome is fairly poor. For many people with metastatic brain tumors, the cancer spreads to other areas of the body. Death often occurs within 2 years.
Call your health care provider if you develop a persistent headache that is new or different for you.
Maity A, Pruitt AA, Judy KD, Phillips PC, Lustig R. Cancer of the central nervous system. In: Abeloff MD, Armitage JO, Niederhuber JE, Kastan MB, McKenna WG, eds. Abeloff’s Clinical Oncology. 4th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2008:chap 70.
Nguyen TD, Abrey LE. Brain metastases: old problem, new strategies. Hematol Oncol Clin North Am. 2007;21(2):369-388.
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