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Ethylene glycol intoxication - Symptom

Alternative Names

Intoxication - ethylene glycol; Ethylene glycol poisoning

Symptoms:

The first symptom of ethylene glycol ingestion is similar to the feeling caused by drinking alcohol (ethanol). Within a few hours, more toxic effects become apparent. Symptoms may include nausea, vomiting, convulsions, stupor, or even coma.

An overdose of ethylene glycol can damage the brain, lungs, liver, kidneys, and lungs. The poisoning causes disturbances in the body's chemistry, including metabolic acidosis. The disturbances may be severe enough to cause profound shock, organ failure, and death.

As little as 120 milliliters (approximately 4 fluid ounces) of ethylene glycol may be enough to kill an average-sized man.

Signs and tests:

Ethylene glycol toxicity should be suspected in anyone who is severely ill after drinking an unknown substance, especially if they at first appear drunk and do not have a smell of alcohol on their breath.

Diagnosis of ethylene glycol toxicity is usually made through a combination of blood, urine, and other tests such as:

Tests will show increased levels of ethylene glycol, blood chemical disturbances, and possible signs of kidney failure and muscle or liver damage.

  • Reviewed last on: 2/2/2011
  • Eric Perez, MD, Department of Emergency Medicine, St. Luke's-Roosevelt Hospital Center, New York, NY. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Ford MD, Clinical Toxicology. 1st ed. Philadelphia, Pa: WB Saunders; 2001.

Marx J. Rosen’s Emergency Medicine: Concepts and Clinical Practice. 6th ed. St. Louis, Mo: Mosby; 2006.

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